CALL FOR PAPERS NextGen Sequencing Technology-based Dissection of Physiological Systems Intrauterine calorie restriction affects placental DNA methylation and gene expression
نویسندگان
چکیده
Pao-Yang Chen, Amit Ganguly, Liudmilla Rubbi, Luz D. Orozco, Marco Morselli, Davin Ashraf, Artur Jaroszewicz, Suhua Feng, Steve E. Jacobsen, Atsushi Nakano, Sherin U. Devaskar, and Matteo Pellegrini Institute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan; Department of Pediatrics, Division of Neonatology and Developmental Biology, Neonatal Research Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California; Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, California; Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, California; Molecular Biology Institute, University of California, Los Angeles, California; Jonsson Comprehensive Cancer Center, Los Angeles, California; and Institute of Genomics and Proteomics, University of California, Los Angeles, California
منابع مشابه
Intrauterine calorie restriction affects placental DNA methylation and gene expression.
Maternal nutrient restriction causes the development of adult onset chronic diseases in the intrauterine growth restricted (IUGR) fetus. Investigations in mice have shown that either protein or calorie restriction during pregnancy leads to glucose intolerance, increased fat mass, and hypercholesterolemia in adult male offspring. Some of these phenotypes are shown to persist in successive genera...
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